1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity related to bortezomib, a proteasome inhibitor Employed in the procedure of various myeloma. Its synthesis or study is crucial for making sure the purity and security of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the treatment of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound during the synthesis of imatinib, a drug that targets precise forms of cancer, together with Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers for instance breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their research is crucial for optimizing the creation process and making certain large purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to deal with breast most cancers, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Utilized in the treatment of breast cancer. Many intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain 6-broMo-2-chloro-8-cyclopentyl-5-Methylpyrido[2 Acid (CAS NO. 949023-sixteen-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers such as ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and tiny mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is linked to the synthesis of adamantane derivatives, that have various applications, which includes antiviral Houses.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme 2' DPP-4 to regulate blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is involved with the synthesis of assorted gluconic acid derivatives, which are used in food, pharmaceutical, and industrial applications.
Canagliflozin Intermediate two: A precursor inside the synthesis of canagliflozin, a medication utilised to handle sort 2 diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).